Kinetics of glucose transport in human erythrocytes.
نویسندگان
چکیده
منابع مشابه
Inhibition by nucleosides of glucose-transport activity in human erythrocytes.
The interaction of nucleosides with the glucose carrier of human erythrocytes was examined by studying the effect of nucleosides on reversible cytochalasin B-binding activity and glucose transport. Adenosine, inosine and thymidine were more potent inhibitors of cytochalasin B binding to human erythrocyte membranes than was D-glucose [IC50 (concentration causing 50% inhibition) values of 10, 24,...
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The present study of the kinetics of the inhibition of K transport in glycoside-poisoned human red cells has been undertaken in an effort to throw more light on the detailed mechanism by which K enters the normal cell. In 1953, Schatz-mann (1) reported that cardiac glycosides inhibitied in a marked manner the uptake of K at 37°C. by red cells which had been depleted of intracelluiar K by cold s...
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Rat erythrocytes with five different amounts of Na+ content have been prepared by using a new, nondetrimental Na+-loading method (net NaHPO4-influx through the anion carrier). This method allowed the determination of 1) maximal translocation rates and apparent dissociation constants for internal Na+ of the Na+-K+ pump, outward Na+-K+ cotransport, and Na+-Li+ countertransport and 2) rate constan...
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The last step of detoxification of both endogenous and environmental toxicants is typically a conjugation that produces a bulky hydrophilic molecule. The excretion of such conjugates out of cells is of sufficient biological importance to have led to the evolution of ATP-driven export pumps for this purpose. The substrate specificity of such transporters is broad, and in some cases it has been s...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1983
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1983.sp014720